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Provigil Class Medication :: Herbal Replacement For Provigil

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In some cases, the brand-name drug and the generic version may be available in different forms and strengths. Provigil can cause mild or serious side effects. The following list contains some of the key Provigil Storage effects that may occur while taking Provigil.

This list does not include all possible side effects. For more information on the possible side Provigil Storage of Provigil, or tips on how to deal with a troubling side effect, talk with your doctor or pharmacist. Call your doctor right away if you have serious side effects. Serious side effects and their symptoms can include the following:. In rare cases, Provigil can cause a severe rash within the first few weeks of taking it. It may occur along with vomiting and fever, and may lead to problems with the liver, lungs, kidneys, and heart.

If you develop a rash while taking Provigil, call your doctor right away. These effects are more likely to happen in people with a heart condition or high blood pressure, but can occur in people without heart conditions. Symptoms can include:. If have these side effects, talk to your doctor Provigil Storage away. Your doctor may need to check you for heart conditions, or monitor your heart rate and blood pressure.

In some cases, these side effects can become severe. Although rare, some people have had thoughts of suicide, symptoms of psychosis such as delusions or hallucinationsmania, and aggression. These side effects are more likely to happen in people who have had mental health problems in the past. If you or someone you know is having thoughts of suicide, a prevention hotline can help. The National Suicide Prevention Lifeline is available 24 hours per day at During a crisis, people who are hard of hearing can use their preferred relay service or dial then Click here for more links and local resources.

Taking Provigil long-term may increase the risk of developing psychological and physical Sotrage. Provigil abuse is not common. Before you drive while taking Provigil, wait until you know how the drug will affect you. Although Provigil helps reduce sleepiness in people with narcolepsy or other conditions, it may not provide full wakefulness.

In addition, Provigil might cause certain side effects, such as dizziness or confusion, that may impair your ability to drive. Provigil is FDA-approved for improving daytime sleepiness caused Proivgil the following medical conditions:. Provigil is sometimes used off-label for uses that are not FDA-approved. Off-label use means Stirage drug has been approved for one use, but is used for another. In other cases, Provigil may be misused for purposes that are not approved.

Provigil is used off-label to treat attention deficit-hyperactivity disorder ADHD. Although some research shows that it can improve symptoms of ADHD, other research shows no benefit. Taking Provigil along with antidepressants has been shown to improve symptoms of fatigue Provigil Storage excessive tiredness in people who have depression.

Provigil is sometimes prescribed off-label to treat symptoms of fatigue caused by conditions such Generic Release Provigil multiple sclerosis MS.

An analysis of clinical studies showed that Provigil can improve symptoms of fatigue in people with MS. Provigil is not usually prescribed off-label for treating anxiety. However, some people say that Provigil gives them more focus, calm, and confidence in social or stressful situations. Because Provigil Storage this, Provigil may be misused for treating social anxiety or performance anxiety. Provigil Storage you have anxiety, talk with your doctor about what treatment Provigio that might reduce your symptoms.

Provigil can cause loss of appetite in some people who take it. Because of this side effect, some people misuse Provigil as a weight loss aid. Misusing this drug Procigil lead to abuse Sforage dependence. The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you.

Your doctor will determine the best dosage to suit your needs. For daytime sleepiness caused by narcolepsy or obstructive sleep apnea, the Provigil Storage вернемся Who Makes Provigil отличная is mg once a day in Procigil morning.

Higher doses are sometimes used, up to mg daily. However, these doses may not be any more effective than mg daily. For excessive sleepiness due to shift work sleep disorder, the typical dosage is mg taken about one hour before the start of your work shift. If you have severe liver problems, your doctor will likely prescribe a lower dosage. The recommended dosage for people with this condition is typically mg daily.

Seniors may Prvoigil more sensitive to the effects of Provigil, especially side effects. If you miss a dose, take it as soon as you remember. Yes, Provigil is usually taken long-term by people with narcolepsy or sleep apnea. These are chronic conditions that often require long-term treatment to improve Provigil Storage of daytime sleepiness. You can take Provigil with or without food. If the drug upsets your stomach, taking it with food might reduce this side effect.

However, if you take it with food, Provigil might take Provihil longer to start Provigi. Provigil tablets should not be crushed or split. Although Provigil is a stimulant, its chemical makeup is different from the makeup of other stimulants, such as amphetamines. This includes Provigil. For instance, the National Collegiate Athletic Association lists stimulants such as Provigil as prohibited during sports. Provigil can interact with several other medications. It can also interact with certain supplements as well as certain foods.

Provigil Storage interactions can cause different effects. For instance, some can interfere with how well a drug works, while Provigil Storage can cause increased side effects.

Below is a list of medications that Provigil Storage interact with Provigil. This list does not contain all drugs that may interact with Provigil. Before taking Provigil, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take.

Also tell them about any vitamins, herbs, and supplements you use. Sharing this information Provigul help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Several Provigil Storage can lessen the activity of an enzyme called cytochrome P 3A4 in your body. Stoage these drugs with Provigil can cause your body to get rid of Provigil more slowly. This can cause more Provigil side effects. Provigil can increase the activity of Storag enzyme called cytochrome P 3A4 in your body. This Storwge cause your body to get rid of certain medications more quickly. As a result, these medications may become less effective. Provigil can reduce the activity of Provigil Storage called cytochrome Provigil Storage 2C19 in your body.

This can cause your body Storag get rid of certain medications more slowly. This may cause more medication side effects. Many other Prpvigil may be affected when taken with Provigil. If you take other medications, talk to your doctor and pharmacist about how to avoid potential interactions.

Modafinil: MedlinePlus Drug Information

Taking Provigil with monoamine oxidase inhibitors MAOIs might lead to dangerous side effects such as very high blood pressure, chest Provigil Gastrointestinal, severe headache, and increased body temperature.

Provigil should not be taken within 14 days of using an MAOI. Taking Provigil with warfarin Coumadin, Jantoven may make your body get rid of warfarin more slowly. Provigil Storage may increase the effects of warfarin and increase your risk of side effects such as bleeding. Provigil may interact with Shorage supplements or herbal products you may be taking. Examples of these include:. Taking Provigil with marijuana might change how marijuana affects you.

Provigil alters enzymes in your body that control how quickly the Provigil Storage gets rid of marijuana chemicals that cause you to get high. Storags might increase or decrease the effects and side effects of marijuana. Drinking certain fruit juices, such as grapefruit Porvigil and Stotage juice, while taking Provigil might change how your body handles the drug.

This could increase the amount of Provigil in your body and increase your risk of side effects. Caffeine in foods and Privigil might add to the stimulant effects of Provigil. This can increase the risk of stimulant-related side Provigik such as anxiety, nervousness, trouble sleeping, and others. Alcohol can make you feel tired and sleepy. This can decrease the effects of Provigil, which is typically Sotrage to help you feel less tired and sleepy. Some people who take Provigil can have changes in mood or thinking that makes them feel Provigil Storage focused and more confident.

Although not common, some people may also experience feelings of euphoria. Provigil Storage effect can lead to misuse or abuse of Provigil for Stogage uses.

Abuse or misuse is more likely to occur in people who have abused alcohol or drugs in the past. Other drugs are available that can treat your condition. Some may be better suited for you than others. Examples of other medications that can be used to decrease daytime Provigil Storage in people with narcolepsy, sleep apnea, or shift work sleep disorder include:.

You may wonder how Provigil compares to certain drugs such as Nuvigil. Provigil and Nuvigil are very similar medications. That means that their chemical makeup is virtually identical, but the chemicals are arranged slightly differently. Provigil and Nuvigil are Storqge first-choice medication options for decreasing sleepiness in people Provigil Storage narcolepsy, sleep apnea, and shift work sleep disorder. That said, an analysis of clinical studies indicates that Provigil and Nuvigil might work about equally well for reducing sleepiness for people with sleep apnea.

Provigil and Nuvigil are both brand-name drugs. The generic name of Nuvigil is armodafinil. Generic drugs are typically less expensive than brand-name drugs. The brand and generic versions of Provigil appear to be more expensive than the brand and generic versions of Nuvigil. Whichever drug you take, the amount you pay will depend on your health insurance plan. You may wonder how Provigil compares to certain drugs such as Vyvanse. Provigil and Vyvanse lisdexamfetamine are both stimulant medications, but they affect the brain in slightly different ways.

Provigil increases wakefulness and alertness. Vyvanse can cause wakefulness and, in people with attention deficit hyperactivity disorder ADHDcan also produce feelings of calm and focus. Provigil is FDA-approved for treating daytime sleepiness caused by narcolepsy, sleep apnea, and shift work sleep disorder.

In some studies, modafinil was also partially discriminated as stimulant-like. Storqge should be observed for signs of misuse or abuse e. The abuse potential of modafinil, and mg was assessed relative to methylphenidate 45 and 90 mg Provigil Storage an inpatient study in individuals experienced with drugs of abuse. Results from this clinical study demonstrated that modafinil produced psychoactive and euphoric effects and feelings consistent with other scheduled CNS stimulants methylphenidate.

In one placebo-controlled clinical trial, the effects of modafinil withdrawal were monitored following 9 weeks of modafinil use. There were no reported withdrawal symptoms with modafinil during 14 days of observation, although sleepiness returned in narcoleptic patients.

In addition, several intentional acute overdoses occurred; the two largest being mg and mg Sttorage by two subjects participating in foreign depression studies. None of these study subjects experienced any unexpected or life-threatening effects.

Adverse reactions that Provlgil reported at these doses included excitation or agitation, Provigil Storage, and slight or moderate elevations in hemodynamic parameters. Other observed high-dose effects in clinical studies have included anxiety, irritability, aggressiveness, confusion, nervousness, tremor, palpitations, sleep disturbances, nausea, diarrhea, and decreased prothrombin time. From postmarketing experience, there have been reports of fatal overdoses involving modafinil Provjgil or in combination with other drugs.

Symptoms most often accompanying Provigil Storage overdose, alone or in combination with other drugs have included insomnia; central nervous Provigil Storage symptoms such as restlessness, disorientation, confusion, agitation, anxiety, excitation, and hallucination; digestive changes Provigil Storage as nausea and diarrhea; and cardiovascular changes such as tachycardia, bradycardia, hypertension, and chest pain.

The child remained stable. The symptoms associated with overdose in children were similar to those observed in adults. Such overdoses Provogil be managed with primarily supportive care, including cardiovascular monitoring. Modafinil is a racemic compound. Modafinil is a white to off-white, crystalline powder that is practically insoluble in water and cyclohexane. It is sparingly to slightly soluble in methanol and acetone. PROVIGIL tablets contain mg or mg of modafinil and the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, and pregelatinized starch.

The mechanism s through which modafinil promotes wakefulness is unknown. Modafinil has wake-promoting actions similar to sympathomimetic agents including amphetamine and methylphenidate, although the pharmacologic profile is not identical to that of the sympathomimetic amines. Modafinil is not a direct- or indirect-acting dopamine receptor agonist. However, in vitro, modafinil binds to the dopamine transporter and inhibits dopamine reuptake. This activity has been associated in vivo with increased extracellular dopamine levels in some brain regions of animals.

In genetically engineered mice lacking the dopamine transporter DATmodafinil lacked wake-promoting activity, suggesting that this activity was DAT-dependent. However, the wake-promoting effects of modafinil, unlike those of amphetamine, were not antagonized by the dopamine receptor antagonist haloperidol in rats.

In addition, alpha-methyl-p-tyrosine, a dopamine synthesis inhibitor, blocks the action of amphetamine, but does not block locomotor activity induced by modafinil. In the cat, equal wakefulness-promoting doses of methylphenidate and amphetamine increased neuronal activation throughout the brain. Modafinil at an equivalent wakefulness-promoting dose selectively and prominently increased neuronal activation in more discrete regions of the brain. The relationship of this finding in cats to the effects of modafinil in humans is unknown.

In addition to its wake-promoting effects and ability to increase locomotor activity in animals, modafinil produces psychoactive and euphoric effects, alterations in mood, perception, thinking, and Provigil Storage typical of other CNS stimulants in humans.

Modafinil has reinforcing properties, Proviigl evidenced by its self-administration in monkeys previously trained to self-administer cocaine; modafinil was Provigil Storage partially discriminated as stimulant-like. The Provigil Storage enantiomers of modafinil have similar pharmacological actions in animals. Two major metabolites of modafinil, modafinil acid and modafinil sulfone, do not appear to contribute to the CNS-activating properties of modafinil.

Modafinil is a racemic compound, whose enantiomers have different pharmacokinetics e. The enantiomers do not interconvert. At steady state, total exposure to R-modafinil is approximately three times that for S-modafinil. The effective elimination Provigil Storage of modafinil after multiple doses is about 15 hours. Apparent steady states of total modafinil and R-modafinil are reached after days of dosing. Food has no effect on overall PROVIGIL bioavailability; however, time to reach peak concentration t max may be delayed by approximately one hour if taken with food.

Urine alkalinization has no effect on the elimination of modafinil. Metabolism occurs through hydrolytic deamidation, S-oxidation, aromatic ring hydroxylation, and glucuronide conjugation.

The largest fraction of the drug in urine was modafinil acid, but at least six other metabolites were present in lower concentrations.

Only two metabolites reach appreciable concentrations in plasma, i. Go here preclinical models, modafinil acid, modafinil sulfone, 2-[ diphenylmethyl sulfonyl]acetic acid and 4-hydroxy modafinil, were inactive or did not appear to mediate the arousal effects of modafinil.

In adults, decreases in trough levels of modafinil have sometimes been observed after multiple weeks of dosing, действительно.

Where To Buy Provigil Online Usa прощения auto-induction, but the magnitude of the decreases and the inconsistency of their occurrence suggest that their clinical significance is minimal. Significant accumulation of modafinil sulfone has been observed after multiple doses due to its long elimination half-life of 40 hours.

Due to potential effects from the multiple concomitant medications with which most of the patients were being treated, the apparent difference in modafinil pharmacokinetics may not be attributable solely to the Prrovigil of aging.

However, the results Provigil Storage that the clearance of modafinil may be reduced in the elderly [see Dosage and Administration 2. Provlgil pharmacokinetics and metabolism of modafinil were examined in patients with cirrhosis of the liver 6 men and 3 women.

Clinically 8 of 9 patients were icteric and all had ascites. In vitro data also demonstrated that modafinil produced an apparent concentration-related suppression of expression of CYP2C9 activity.

Other CYP activities did not appear to be affected by modafinil. The existence of multiple pathways for modafinil metabolism, as well as the fact that a non-CYP-related pathway is the most rapid in metabolizing modafinil, suggest that there is a low probability of substantive effects on the overall pharmacokinetic profile of PROVIGIL due to CYP inhibition by concomitant medications.

There was no Stoage of tumorigenesis associated with modafinil administration in these studies. However, the mouse study was inadequate because the high dose was not a maximum tolerated dose MTD. Modafinil was negative in a series of in vitro i. The criteria for narcolepsy include either: 1 recurrent Provigil Storage naps or lapses into sleep that occur almost daily for at least three months, plus sudden bilateral loss of postural muscle tone in association with intense emotion cataplexy ; or 2 a complaint of excessive sleepiness or sudden muscle weakness with associated features: sleep paralysis, hypnagogic hallucinations, automatic behaviors, disrupted major sleep episode; and polysomnography demonstrating one of the following: sleep latency less than 10 minutes or rapid eye movement REM sleep latency less than 20 minutes.

For entry into these studies, all patients were required to have objectively documented excessive Provigiil sleepiness, via a Multiple Sleep Latency Test MSLT with two or more sleep onset REM periods and the absence of any other clinically significant active medical or psychiatric disorder. For each test session, Provigil Storage subject was told to lie quietly and attempt to sleep. Each test session was terminated after 20 minutes if no sleep occurred or 15 minutes after sleep onset.

For a successful trial, both measures had to show statistically significant improvement. The MWT measures latency in minutes to sleep onset averaged over 4 test sessions at 2 hour intervals following nocturnal polysomnography. For each test session, the subject was asked to attempt to remain awake without using extraordinary measures. Each test session was terminated after 20 minutes if no sleep occurred or 10 minutes after sleep onset.

Patients were rated by evaluators who had no access to any data about the patients other Stoorage a measure of their baseline severity. Evaluators were not given any specific guidance about the criteria they were to apply when rating patients. Both studies demonstrated improvement in objective and Proviigil measures of excessive daytime sleepiness for both the mg and mg doses compared to placebo.

The criteria include either: 1 excessive sleepiness or insomnia, plus Provigil Storage episodes of impaired breathing during sleep, and associated features such as loud snoring, morning headaches and dry mouth upon awakening; or 2 excessive sleepiness or insomnia and polysomnography demonstrating one of the following: more than five obstructive apneas, each greater than 10 seconds in duration, per hour of sleep and one or more of the following: frequent arousals from sleep Proivgil with the apneas, bradytachycardia, and arterial oxygen desaturation in association with the apneas.

CPAP use continued throughout the study. The primary Provigil Storage of effectiveness was the change from baseline on the ESS at final visit. At week 4, the ESS was reduced by 4. All patients met the criteria for chronic SWD. The criteria Provigil Storage 1 either, a a primary complaint of excessive sleepiness or insomnia which is temporally associated with a work period usually night work that occurs during the habitual sleep phase, or b polysomnography and the MSLT demonstrate loss of a normal sleep-wake pattern i.

It should be noted that not all Provigil Storage with a complaint of sleepiness who are also engaged in shift work meet the criteria for Provigil Storage diagnosis of SWD. In the clinical trial, only patients who were symptomatic for at least 3 months were enrolled. Advise patients to stop taking PROVIGIL and to notify their physician right away if they develop a rash, hives, mouth sores, blisters, peeling skin, trouble swallowing or breathing, or a related allergic phenomenon.

Provigil Storage patients not to alter their previous behavior with regard Provigil Storage Porvigil dangerous activities e. Inform patients that it may be critical that they continue to take their previously prescribed treatments e. Advise patients to stop taking PROVIGIL and contact their physician right away if they experience chest pain, rash, depression, anxiety, or signs of psychosis or mania. Advise patients первом Nuvigil Vs Provigil Adhd почему notify their physician if they become pregnant or intend to become pregnant during therapy.

Caution patients regarding the potential increased risk of pregnancy when using steroidal contraceptives including depot or implantable contraceptives with PROVIGIL and for one month after discontinuation of therapy. There may be new information. This information does not take the place of talking with your doctor about your medical Storag or treatment.

PROVIGIL may cause serious side effects including a serious rash or a serious allergic Provigil Storage that may affect parts of your body such as your liver or blood cells. Any of these may need to be treated in a hospital and may be life-threatening. If you have a severe rash with PROVIGIL, stopping the medicine may not keep the rash from becoming life-threatening or causing you to Provigil Storage permanently disabled or disfigured.

PROVIGIL is a prescription medicine used to improve wakefulness in adults who are very sleepy due to one of the following diagnosed sleep disorders:. Follow your doctor's advice about good sleep habits and using other treatments. Tell your doctor if you have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

Tell Provigil Storage doctor about all of your medical conditions including, if you:. Tell your Provigil Storage about all the medicines Provigil Storage takeincluding prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you Provigil Storage. Keep a list of them and show it to your doctor and pharmacist when you get a new medicine. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide.

It may harm them and it is against the law. If you would like Provigil Storage information, talk with your Probigil. For more Provigil Storage, call Inactive Ingredients: lactose monohydrate, microcrystalline cellulose, pregelatinized starch, croscarmellose sodium, povidone, and magnesium stearate.

Rx only teva. DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this Provigil Storage through its RSS feed.

Provigil (modafinil)

DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. Due to inconsistencies between the drug labels on Provigil Storage and the pill images provided by RxImagewe no longer display the RxImage pill images associated with drug labels.

We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. View Package Photos. Drug Label Info. NDC National Drug Code - Each drug product is assigned this unique number which can be found on the drug's outer packaging.

Approval: Provigil Storage following serious adverse reactions are described elsewhere in the labeling: Serious Rash, including Stevens-Johnson Syndrome [see Warnings and Precautions 5. Table 1. Cardiovascular: Stroke Hematologic: agranulocytosis Psychiatric disorders: psychomotor hyperactivity.

This medicinal product does not require any special storage conditions. Nature and contents of container. Opaque PVC/PVDC/aluminium blisters. Packs of Provigil (Modafinil) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, Storage. Store at 20°°C (68°°F).

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